Particle Analysis for Biopharmaceuticals – an Overview from Protein Particles to Living Cells

Analytical technologies, ATMPs, Particle characterization, Protein aggregation
Particle analysis for biopharmaceuticals – an overview from protein particles to living cells

In this webinar, Dr. Tim Menzen will introduce you to the broad field of particle characterization for biopharmaceuticals. He will outline the various types of particles relevant in biopharmaceutical industry, ranging from impurities and degradation products like protein aggregates to particulate formulations such as viral vectors and living cells. His talk will further present analytical tools available for the characterization of particles in various size ranges. On the example of real case studies, Dr. Menzen will describe, how a broad analytical portfolio of orthogonal methods is used for the reliable sizing, quantification, differentiation and identification of particles in the nanometer, micrometer and visible size range.

You will learn about…

  • the various types of particles relevant for the biopharmaceutical industry
  • different analytical techniques and their applications during drug product development
  • the portfolio of analytical tools relevant for biopharmaceutical applications
  • the results of 3 case studies solving important analytical challenges:
    • Differentiation of protein aggregates from silicone oil droplets
    • Quantification of empty vs. full capsids in AAV samples
    • Identifying impurities in cell-based medicinal products

The duration of this webinar is 1 hour and will include an extended Q&A session.

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Dr. Tim Menzen

Dr. Tim Menzen

Speaker

Dr. Tim Menzen is Chief Technology Officer (CTO) of Coriolis Pharma. He is a pharmacist by training and received his PhD from the Ludwig Maximilian University (LMU) of Munich, Germany. Dr. Menzen joined Coriolis Pharma in 2014 and is responsible for internal research projects at Coriolis and scientific relations, including collaborations with partners from industry and academia. He has co-authored more than 20 publications including book chapters and articles in peer-reviewed journals.

Dr. Daniel Weinbuch

Dr. Daniel Weinbuch

Webinar Host

Dr. Daniel Weinbuch will be your host during this webinar. He holds a PhD in BioPharmaceutical Sciences from the Leiden University (The Netherlands). His research focused on the topic “pharmaceutical aspects of subvisible particles in protein formulations”, where he (co-)authored eight peer-reviewed publications. Dr. Weinbuch joined Coriolis in 2013 and is now part of the Business Development Unit.

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