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Featured service Formulation development for virus-based ATMPs

Receive a robust and tailor-made formulation for your gene- or cell therapy product.

About us

Coriolis is a globally operating service provider and one of the world leaders in formulation research and development of (bio)pharmaceutical drugs and vaccines.

As a privately-held and independent company with an interdisciplinary team of highly skilled scientists and an expert scientific advisory board, we provide cutting-edge services and tailor-made solutions for our clients.

Formulation Development

“It is a medicine, not a molecule, that we are giving to the patient” Marc B. Brown, 2005.

Coriolis is the expert in developing liquid and lyophilized formulations for a large variety of different (bio)pharmaceutical molecules, including proteins, peptides, nucleic acids, ATMPs, GMOs, vaccines and virus(-like) particles.

Find out how we can support your drug development...

Analytical Services

A highly diverse analytical portfolio entirely performed in-house: This is Coriolis.

With the latest in technology and highly experienced scientists, we are a trendsetter in the field. We provide our analytical services for samples up to biosafety level S2 under R&D and cGMP conditions, including method development, qualification and validation.

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About us

Independent, reliable and always on the cutting edge of science. Coriolis is a leading service provider for formulation research and development of (bio)pharmaceutical drugs and vaccines.

Get to know us...

2021/10/05

A Sunny Sailing Trip at the Starnberg Lake

Coriolis employees enjoyed a wonderful sailing day with the Coriolis-sponsored GFK Team on the H-boat "Kiaora"

2021/10/04

Meet us at the PEGS Europe Summit in Barcelona

Find us at booth 210 and listen to our Scientific Advisor Prof. Kersten's talk about "mRNA-Based COVID-19 Vaccines"

2021/09/13

Coriolis supports live discussion forum BioM Science & Health

The BioM Forum is an interdisciplinary discussion platform making scientific viewpoints available to the public. Coriolis is gold sponsors of the next session about mRNA and gene therapy.

2021/09/08

Prof. Dr. Susumu Uchiyama joins Scientific Advisory Board of Coriolis

We welcome Prof. Dr. Susumu Uchiyama as a new Scientific Advisory Board Member and expert for viral vectors for gene therapy.

2021/09/06

Coriolis-sponsored sailing team happy with 2021 world cup race

The GFK racing team achieved a fantastic 10th place at the H-boat world cup race in Denmark.

2021/08/31

In Memoriam Prof. Dr. Wim Jiskoot (1961 – 2021), Scientific Advisor of Coriolis

We will remember Wim as the openminded, brilliant, and honest person, who stayed positive even after a devastating diagnosis. Our thoughts are with his loved ones, in particular Karin, Julia and Carles.

2021/08/03

Coriolis Scientist contributes to "Bioanalytik" by Lottspeich

Our AUC expert Dr. Klaus Richter co-authors chapter about protein interactions in Lottspeich's standard reference book "Bioanalytik"

2021/07/22

Coriolis helps victims of flood catastrophe

Coriolis supports the emergency aid by Germany's Relief Coalition with donation. Our thoughts are with those who lost relatives and friends.

2021/07/05

Prof. Dr. Olivia Merkel joins our Scientific Advisory Board

We welcome Prof. Dr. Olivia Merkel as a new Scientific Advisory Board Member and expert for targeted mRNA delivery

2021/06/22

Coriolis Supports Local Sailing Team on „Road to Sweden 2023” Project

The ambitious goal of the GFK sailing team is a top ten rank in the world championship in 2023.

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Latest publications

Towards quantification and differentiation of protein aggregates and silicone oil droplets in the low micrometer and submicrometer size range by using oil-immersion flow imaging microscopy and convolutional neural networks

Muhammad Umar, Nils Krause, Andrea Hawe, Friedrich Simmel and Tim Menzen

Stress Factors in Protein Drug Product Manufacturing and Their Impact on Product Quality

Tapan K.Da, Alavattam Sreedhara, James D. Colandene, Danny K. Chou, Vasco Filipe, Christoph Grapentin, Jim Searles, Twinkle R. Christian, Linda O. Narhi and Wim Jiskoot

Comparison of Syringes With Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates in Brolucizumab, Aflibercept and Bevacizumab

Marc Schargus, Katharina Tatjana Kopp, Constanze Helbig, Andreas Frings, and Gerhard Winter

Forced degradation of cell-based medicinal products guided by flow imaging microscopy: explorative studies with Jurkat cells

A D Grabarek, W Jiskoot, A Hawe, K Pike-Overzet, T Menzen

Protein-Protein Interaction

Peter Uetz, Eva-Kathrin Ehmoser, Dagmar Klostermeier, Klaus Richter & Ute Curth.
Editors: Jens Kurreck, Joachim Engels & Friedrich Lottspeich.

Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors

Ruth Rieser, Johanna Koch, Greta Faccioli, Klaus Richter, Tim Menzen, Martin Biel, Gerhard Winter, Stylianos Michalakis

Combining Unfolding Reversibility Studies and Molecular Dynamics Simulations to Select Aggregation-Resistant Antibodies

Berner C, Menzen T, Winter G, Svilenov HL.

mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

Schoenmaker L, Witzigmann D, Kulkarni JA, Verbeke R, Kersten G, Jiskoot W, Crommelin DJA

Formulation of Cell-Based Medicinal Products: A Question of Life or Death?

Karin H Hoogendoorn, Daan J A Crommelin, Wim Jiskoot

Addressing the Cold Reality of mRNA Vaccine Stability.

Daan J A Crommelin, Thomas J Anchordoquy, David B Volkin, Wim Jiskoot, Enrico Mastrobattista

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