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Open access webinar Particle analysis for biopharmaceuticals

Coriolis CTO Dr. Tim Menzen will introduce you to the broad field of particle characterization and discuss real life case studies.

About us

Coriolis is a globally operating service provider and one of the world leaders in formulation research and development of (bio)pharmaceutical drugs and vaccines.

As a privately-held and independent company with an interdisciplinary team of highly skilled scientists and an expert scientific advisory board, we provide cutting-edge services and tailor-made solutions for our clients.

Formulation Development

“It is a medicine, not a molecule, that we are giving to the patient” Marc B. Brown, 2005.

Coriolis is the expert in developing liquid and lyophilized formulations for a large variety of different (bio)pharmaceutical molecules, including proteins, peptides, nucleic acids, ATMPs, GMOs, vaccines and virus(-like) particles.

Find out how we can support your drug development...

Analytical Services

A highly diverse analytical portfolio entirely performed in-house: This is Coriolis.

With the latest in technology and highly experienced scientists, we are a trendsetter in the field. We provide our analytical services for samples up to biosafety level S2 under R&D and cGMP conditions, including method development, qualification and validation.

Get to know our services...

About us

Independent, reliable and always on the cutting edge of science. Coriolis is a leading service provider for formulation research and development of (bio)pharmaceutical drugs and vaccines.

Get to know us...

2021/11/17

Coriolis AUC Expert gives Talk at the Gene and Cell Therapy Conference

Dr. Klaus Richter will speak about "Assessing Critical Quality Attributes of viral vectors for gene therapy" at conference in Munich.

2021/11/05

Meet us at the Festival of Biologics in Basel

Fund us at booth 51 and arrange your face-to-face meeting with our experts on site.

2021/10/05

A Sunny Sailing Trip at the Starnberg Lake

Coriolis employees enjoyed a wonderful sailing day with the Coriolis-sponsored GFK Team on the H-boat "Kiaora"

2021/10/04

Meet us at the PEGS Europe Summit in Barcelona

Find us at booth 210 and listen to our Scientific Advisor Prof. Kersten's talk about "mRNA-Based COVID-19 Vaccines"

2021/09/13

Coriolis supports live discussion forum BioM Science & Health

The BioM Forum is an interdisciplinary discussion platform making scientific viewpoints available to the public. Coriolis is gold sponsors of the next session about mRNA and gene therapy.

2021/09/08

Prof. Dr. Susumu Uchiyama joins Scientific Advisory Board of Coriolis

We welcome Prof. Dr. Susumu Uchiyama as a new Scientific Advisory Board Member and expert for viral vectors for gene therapy.

2021/09/06

Coriolis-sponsored sailing team happy with 2021 world cup race

The GFK racing team achieved a fantastic 10th place at the H-boat world cup race in Denmark.

2021/08/31

In Memoriam Prof. Dr. Wim Jiskoot (1961 – 2021), Scientific Advisor of Coriolis

We will remember Wim as the openminded, brilliant, and honest person, who stayed positive even after a devastating diagnosis. Our thoughts are with his loved ones, in particular Karin, Julia and Carles.

2021/08/03

Coriolis Scientist contributes to "Bioanalytik" by Lottspeich

Our AUC expert Dr. Klaus Richter co-authors chapter about protein interactions in Lottspeich's standard reference book "Bioanalytik"

2021/07/22

Coriolis helps victims of flood catastrophe

Coriolis supports the emergency aid by Germany's Relief Coalition with donation. Our thoughts are with those who lost relatives and friends.

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Latest publications

Continuous milli-scale reaction calorimeter for direct scale-up of flow chemistry

Marlies Moser, Alain G. Georg, Finn L. Steinemann, David P. Rütti and Daniel M. Meier

Minimizing Oxidation of Freeze-Dried Monoclonal Antibodies in Polymeric Vials Using a Smart Packaging Approach

Nicole Härdter, Tim Menzen and Gerhard Winter

Towards quantification and differentiation of protein aggregates and silicone oil droplets in the low micrometer and submicrometer size range by using oil-immersion flow imaging microscopy and convolutional neural networks

Muhammad Umar, Nils Krause, Andrea Hawe, Friedrich Simmel and Tim Menzen

Stress Factors in Protein Drug Product Manufacturing and Their Impact on Product Quality

Tapan K.Da, Alavattam Sreedhara, James D. Colandene, Danny K. Chou, Vasco Filipe, Christoph Grapentin, Jim Searles, Twinkle R. Christian, Linda O. Narhi and Wim Jiskoot

Comparison of Syringes With Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates in Brolucizumab, Aflibercept and Bevacizumab

Marc Schargus, Katharina Tatjana Kopp, Constanze Helbig, Andreas Frings, and Gerhard Winter

Forced degradation of cell-based medicinal products guided by flow imaging microscopy: explorative studies with Jurkat cells

A D Grabarek, W Jiskoot, A Hawe, K Pike-Overzet, T Menzen

Protein-Protein Interaction

Peter Uetz, Eva-Kathrin Ehmoser, Dagmar Klostermeier, Klaus Richter & Ute Curth.
Editors: Jens Kurreck, Joachim Engels & Friedrich Lottspeich.

Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors

Ruth Rieser, Johanna Koch, Greta Faccioli, Klaus Richter, Tim Menzen, Martin Biel, Gerhard Winter, Stylianos Michalakis

Combining Unfolding Reversibility Studies and Molecular Dynamics Simulations to Select Aggregation-Resistant Antibodies

Berner C, Menzen T, Winter G, Svilenov HL.

mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

Schoenmaker L, Witzigmann D, Kulkarni JA, Verbeke R, Kersten G, Jiskoot W, Crommelin DJA

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