WEBINAR: AUC – A real alternative for characterization and QC analysis of biologics, vaccines and gene therapy vectors?
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Analytical Ultracentrifugation (AUC) – A real alternative for characterization and QC analysis of biologics, vaccines and gene therapy vectors?
AUC is a highly versatile analytical method and brings valuable benefits during the research and development of (bio)pharmaceutical drug products.
AUC is based on a simple principle: when (macro)molecules in solution are subject to a centrifugal force, they begin to settle at a certain velocity. With a mathematical correlation between sedimentation behavior and hydrodynamic properties, scientists can determine many critical parameters of a drug substance or drug product for a variety of biopharmaceutical applications, from analyzing small peptides to investigating macromolecular interactions.
In this webinar Klaus Richter talks about AUC as an alternative to traditional methods for the characterization and QC analysis. The application for biologics, vaccines, as well as gene and cell therapy products, will be taken particularly into account.
Learning objectives
- What is the principle of AUC?
- Which questions can be answered by AUC during characterization of biologics (e.g. protein & peptides), vaccines and gene therapy vectors?
- Why moving AUC towards QC testing?
