X-ray powder diffraction (XRD)
X-ray powder diffraction (XRD) is a powerful technique for the determination of the amorphous or crystalline state of a protein in a lyophilized drug product.
XRD is employed during lyophilization process development and supports results obtained from scanning electron microscopy, BET analysis and Karl-Fischer titration in defining optimal freeze-drying conditions. Coriolis Pharma is a leading contract laboratory providing analytical service for physico-chemical characterization for lyophilization development, including XRD.
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