Liquid Drug Product Manufacturing Services
Coriolis Pharma develops and manufactures liquid drug products—including formulation work requiring solvents, co-solvents and excipients selection—and formulation lifecycle management. Additionally, we can manufacture a developed formulation for preformulation, toxicology and proof of concept, as well as lead lot stability studies.
Automated Filling Equipment for Liquid Drug Products
We utilize modern automated filling equipment: the Flexicon FPC50 system, including LAF by Franz Ziel. This state-of-the-art solution is capable of processing all common vial formats and addressing non-GMP batch size needs ranging from a few dozen vials to several thousand.
Coriolis also provides filling solutions for non-vial container formats, including:
- Prefilled syringes
- Cartridges
- Safe-lock tubes
- Cryotubes
- Custom container formats
We offer flexible semiautomated or manual filling solutions for small batches and products up to biosafety level 2.
| Liquid drug product batch size capabilities | |
|---|---|
| 2 ml vials (2R) | 15,000 vials/day |
| 6 ml vials (6R) | 8,000 vials/day |
| 10 ml vials (10R) | 8,000 vials/day |
| 20 ml vials (20R) | 4,000 vials/day |
| 50 ml vials (50R) | 2,000 vials/day |
Liquid Drug Product Manufacturing for Ranging Modalities
Coriolis Pharma’s deep expertise across many biologic modalities, combined with input from world-leading external advisors, offers the knowledge and experience needed to solve even the most complex formulation and drug development challenges. We’ve worked with more than 930 compounds, including drug substances like live virus vaccines, viral vectors or cell therapies that require biosafety level 2.
Your Phase
Our expert team has the expertise and experience to guide your liquid drug product from preclinical and early-phase development to the market.
Liquid Drug Products Resources
Publications
A Model-Based Optimization Strategy to Achieve Fast and Robust Freeze-Drying Cycles
December 1, 2023
Publications
November 1, 2021
Publications
October 1, 2021
Publications
Stress Factors in Protein Drug Product Manufacturing and Their Impact on Product Quality
October 1, 2021
