Higher order structure
With structure comes functionality.
Biologics receive their activity mainly through structure and the higher order structure of a biopharmaceutical molecule is often strongly connected to the quality, stability, safety and efficacy of a therapy. Thus, a detailed understanding of the higher order structure of a biopharmaceutical molecule is crucial deliverable of a complete analytical toolbox. A comprehensive analytical characterization of a molecule's higher order structure, however, requires the use of different orthogonal techniques.
Coriolis offers a large portfolio of instruments and services for the analysis of higher order structures. In consolidation with our clients, we select and develop a set of suitable methods for the specific sample or drug product. This enables the best possible insights into the secondary, tertiary or quaternary structure of the biopharmaceutical molecule. All our analytical techniques are operated in house by our scientific experts.
Explore our particle characterization techniques and get in touch with us to find out how a comprehensive higher order structure analysis can be achieved for your sample.