Robustness testing, scale-up and transfer

lyophilization_development

A robust and scalable process ensures a smooth transfer

The transfer of a lyophilization cycle from Coriolis to the manufacturing site of our clients is a crucial step during development. Thus, our scientists designing and developing freeze-drying cycles to be robust and scalable, allowing for a smooth process transfer.

Lyophilization process transfer

Coriolis operates a 400 m² lyophilization development center with freeze-dryers of various sizes and drying capacities. This allows our scientists to perform freeze-drying cycle development at lab-, pilot- and production-scale, while optimizing processes for scale-up already at an early development stage.

From the very beginning of process development, our experts consider the key variables of the lyophilization process that enable a later scale-up and transfer to the production facilities of our customer.

Our freeze-dryers are equipped with a broad range of the latest in process analytical technology to comprehensively understand all important process characteristics. Also, our scientists utilize a portfolio of dedicated lyo analytics for product characterization. 

Get in contact with our experts today and find out how you can benefit from our lyophilization process development services.

Contact us

Contact us

For enquiries related to lyophilized formulations please contact Dr. Matthias Lucke

Dr. Matthias Lucke