Webinar: Nanoparticulate Impurities in Excipients - A Threat to Protein Stability
Merck Life Science hosts Webinar with Coriolis Scientists
Coriolis CSO Dr. Andrea Hawe and Analytical Service Specialist Dr. Daniel Weinbuch will give a webinar talk about their research on nanoparticulate impurities in pharmaceutical-grade sucrose.
Abstract: A main reason for using excipients is to stabilize the active pharmaceutical ingredient and by that, ensuring an effective and safe therapy. Pharmaceutical grade sucrose, an important and commonly used stabilizer, contains nanoparticulate impurities (NPIs) of 100-200 nm size originating from the starting raw material. In this webinar, the scientists behind the discovery discuss the characteristics of these NPIs, explain their impact on aggregate/particle analytics and show, on the example of antibodies, that NPIs are a threat to protein stability. Their research has triggered the development of improved sucrose grades, that are low in NPIs to reduce the risk of unwanted instability
The event takes place on 5 November at 16:00 (CET). Thereafter, an on-demand version will be available.
Registration for live & on-demand webinar - Click here
Further reading:
- Journal Publications from the research project: Weinbuch et al. 2015 & Weinbuch et al. 2017
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